Are pilot trials useful for predicting randomisation and attrition rates in definitive studies: A review of publicly funded trials.
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| Abstract | :
External pilot trials are recommended for testing the feasibility of main or confirmatory trials. However, there is little evidence that progress in external pilot trials actually predicts randomisation and attrition rates in the main trial. To assess the use of external pilot trials in trial design, we compared randomisation and attrition rates in publicly funded randomised controlled trials with rates in their pilots. |
| Year of Publication | :
2018
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| Journal | :
Clinical trials (London, England)
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| Number of Pages | :
1740774517752113
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| Date Published | :
2018
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| ISSN Number | :
1740-7745
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| URL | :
http://journals.sagepub.com/doi/abs/10.1177/1740774517752113?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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| DOI | :
10.1177/1740774517752113
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| Short Title | :
Clin Trials
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