Warfarin and bosentan interaction in a patient with pulmonary hypertension secondary to bilateral pulmonary emboli.
| Author | |
|---|---|
| Abstract | :
Bosentan is an endothelin-receptor antagonist that reportedly induces both cytochrome P450 (CYP) 3A4 and CYP2C9 enzymes, which are also involved in warfarin metabolism. We present a case report describing a probable drug interaction between warfarin and bosentan in a patient with pulmonary hypertension. |
| Year of Publication | :
2010
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| Journal | :
Clinical therapeutics
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| Volume | :
32
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| Issue | :
1
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| Number of Pages | :
53-6
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| ISSN Number | :
0149-2918
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| URL | :
https://linkinghub.elsevier.com/retrieve/pii/S0149-2918(10)00005-6
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| DOI | :
10.1016/j.clinthera.2010.01.004
|
| Short Title | :
Clin Ther
|
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