Avobenzone incorporation in a diverse range of Ru(II) scaffolds produces potent potential antineoplastic agents.
Author | |
---|---|
Abstract | :
Four structurally distinct classes of polypyridyl ruthenium complexes containing avobenzone exhibited low micromolar and submicromolar potencies in cancer cells, and were up to 273-fold more active than the parent ligand. Visible light irradiation enhanced the cytotoxicity of some complexes, making them promising candidates for combined chemo-photodynamic therapy. |
Year of Publication | :
2020
|
Journal | :
Dalton transactions (Cambridge, England : 2003)
|
Volume | :
49
|
Issue | :
35
|
Number of Pages | :
12161-12167
|
Date Published | :
2020
|
ISSN Number | :
1477-9226
|
URL | :
https://doi.org/10.1039/d0dt02016h
|
DOI | :
10.1039/d0dt02016h
|
Short Title | :
Dalton Trans
|
Download citation |