Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib.
| Author | |
|---|---|
| Abstract | :
Hutchinson-Gilford progeria syndrome (HGPS) is an ultra-rare, fatal, segmental premature aging syndrome caused by the aberrant lamin A protein, progerin. The protein farnesyltransferase inhibitor, lonafarnib, ameliorates some aspects of cardiovascular and bone disease. |
| Year of Publication | :
2018
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| Journal | :
Pediatric research
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| Date Published | :
2018
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| ISSN Number | :
0031-3998
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| URL | :
http://dx.doi.org/10.1038/pr.2018.9
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| DOI | :
10.1038/pr.2018.9
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| Short Title | :
Pediatr Res
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